#Chris hannan synergy wellness trial#

M., Marquis-Gravel, G., Muñoz, D., Re, R. Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial.Conclusions In this prespecified analysis of ADAPTABLE, we found that the relative effectiveness and safety of high- versus low-dose aspirin was not modified by baseline P2Y12 inhibitor use. Overall, dose switching or discontinuation was more common in the high-dose compared with low-dose aspirin group, but the pattern was not modified by P2Y12 inhibitor use. We found no interaction in the relative effectiveness and safety of high- versus low-dose aspirin by P2Y12 inhibitor use. P2Y12 inhibitor use was associated with higher risk of the primary effectiveness end point (10.86% versus 6.31% adjusted hazard ratio, 1.40 ) but was not associated with bleeding (0.95% versus 0.53% adjusted HR, 1.42 ).

Of 13 815 (91.6%) participants with available data, 3051 (22.1%) were receiving clopidogrel (2849 ) or prasugrel (203 ) at baseline. We used multivariable Cox regression to compare the relative effectiveness and safety of aspirin dose within P2Y12 and non-P2Y12 groups. The primary effectiveness end point was a composite of death, myocardial infarction, or stroke and the primary safety end point was major bleeding requiring blood transfusions. Methods and Results Participants in ADAPTABLE were stratified according to baseline use of clopidogrel or prasugrel (P2Y12 group). Whether concomitant P2Y12 inhibitor therapy modifies the effect of aspirin dose on clinical events remains unclear.

#Chris hannan synergy wellness trial#

Vice Provost for Undergraduate Educationīackground The ADAPTABLE (Aspirin Dosing: A Patient-Centric Trial Assessing Benefits and Long-Term Effectiveness) was a large, pragmatic, randomized controlled trial that found no difference between high- versus low-dose aspirin for secondary prevention of atherosclerotic cardiovascular disease.

Office of Vice President for Business Affairs and Chief Financial Officer.

Office of VP for University Human Resources.

Stanford Woods Institute for the Environment.

Stanford Institute for Economic Policy Research (SIEPR).

Institute for Stem Cell Biology and Regenerative Medicine.

Institute for Human-Centered Artificial Intelligence (HAI).

Institute for Computational and Mathematical Engineering (ICME).

Freeman Spogli Institute for International Studies.

Stanford Doerr School of Sustainability.

Together, we can make a difference in the lives of children in out-of-home care in Tasmania. We are incredibly grateful to Fullers Book Shop for their generous support and commitment to making reading a joyful experience for every child. Support positive education outcomes for children in Out of Home Care. Provide access to high-quality literature and promote literacy development. Celebrate birthdays and bring joy to children in foster care.

Ignite a love for reading and open up new worlds for children. This initiative, alongside our Hook into Books campaign, aims to: This partnership directly connects with LWB's Education strategic intentions to equip children and young people in care with the skills and knowledge they need to thrive. This can profoundly impact their educational attainment, future employment prospects, and overall life outcomes. Research shows that children in foster care are significantly more likely to experience difficulties with reading and literacy compared to their peers. The importance of reading and literacy for children in care cannot be overstated. They will kindly donate a book to each of our children in our Out-of-Home Care programs on their birthday in an initiative we are calling a Book for Your Birthday.

Tim Jarvis and the team at Fuller's are on a mission to promote literacy and the love of reading in our community. I’m excited to announce this great initiative between Life Without Barriers Tasmania and Fullers Book Shop Hobart to bring the joy of reading to children in out-of-home care throughout the state! 📚 A Book for Your Birthday: Bringing Joy and Literacy to Tasmanian Children in Out-of-Home Care 📚